Of course, taking medications for life as one must for finasteride and dutasteride for hair loss has never been evaluated for long term safety (decades). The authors raise the alarm, but we need data here. There is a balancing act, to get the immediate benefits of these drugs vs suffer long term ill defined harm yet to be made clear. I don’t know the answer but I thought my readers should be aware that this is a relevant issue for those on long-term use of these drug. In a study of finasteride use over 20 years ago published in the New England Journal of Medicine with men over 55, there was a decreased incidence of prostate cancer in those who took finasteride by 25% compared to a control group. As prostate cancer is the leading cancer in men, this was an impressive finding.