i would like to know your opinion on a medication called
tofacitinib citrate which was used to treat a man with alopecia
universalis, could this work for someone with DUPA seeing that DHT
might not play a part in this hair loss type?
Tofacitinib is a medication to treat rheumatoid arthritis. There was a report by Yale University professor Brett A. King, M.D published in the Journal of Investigative Dermatology that the medication grew hair on an alopecia totalis/ universalis patient.
Alopecia Totalis or Alopecia Universalis is thought to be a condition where the patients own immune system attacks their own hair follicles which results in hair loss. It is hypothesized that the drug diminished or interfered with the immune system attacking the hair follicles. Tofacitinib is not approved for hair loss by the FDA. Tofacitinib will not likely work for genetic androgenic alopecia and there are many safety issues (i.e. infections) with the drug which must be considered.