I’ve read that finasteride reduces something called prostate specific antigen (PSA). What role does PSA have in hair loss? I’ve also read that PSA is a misnomer as it’s not really only in the prostate. This article says that saw palmetto does not lower serum PSA levels: AAFP.org
But propecia does lower PSA levels. Do PSA levels have any relationship to hair loss? In other words, if saw palmetto does work on the prostate but only in the prostate, does it not have any effect on male pattern baldness?
PSA levels should be very low in people without prostate cancer and higher than normal in those with prostate cancer. PSA has nothing to do with hair loss, it is just a protein found in the blood in high concentrations in those with prostate cancer. I have also read articles on saw palmetto that indicate that the mechanism of action is different than finasteride and the fact that it does not impact the PSA levels shows that.
Some people feel that saw palmetto has value in balding prevention, but I really do not know the answer to that point. Not enough studies have been done that have met my satisfaction.