https://www.ncbi.nlm.nih.gov/m/pubmed/14999221/

Abstract

PT-141, a cyclic heptapeptide melanocortin analog, was evaluated following subcutaneous administration to healthy male subjects and to patients with erectile dysfunction (ED) who report an inadequate response to Viagra. An inadequate response was defined for this study by patient report indicating that achievement of an erection suitable for vaginal penetration occurred < or =50% of the time while taking 100 mg Viagra. Erectile responses were assessed by RigiScan in healthy subjects in the absence of visual sexual stimulation (VSS) and in ED patients in the presence of VSS. Doses ranging from 0.3 to 10 mg were administered to healthy male subjects, resulting in a statistically significant erectile response at doses greater than 1.0 mg. ED patients were treated with placebo, 4 or 6 mg PT-141 in a crossover design in the presence of VSS. The erectile response induced by PT-141 was statistically significant at both doses. PT-141 was safe and well tolerated in both studies. The erectogenic potential of PT-141, its tolerability profile and its ability to cause significant erections in patients who do not have an adequate response to a PDE5 inhibitor suggest that PT-141 may provide an alternative treatment for ED with a potentially broad patient base.

After 5 days, a few patients have reported sexual side effects. When that happens, I often tell my patients to stop the medication for a few weeks until everything becomes normal again, and then retry it at one pill every 4 days for 3 weeks, and if that works, increase it to one pill every 3 days for 3 weeks. If that works, try one pill every two days, and stay on this dose, which is 80% as effective as the full dose.

I have seen this many times. Men often glue on bits of their hair just to thicken what they have on their heads. I have seen this from minimal to extensive. This man has done a wonderful job, but how does he maintain this? A wig might be the best answer to his look.

My New Glue On Hair Is Now Stuck On My Head! from tressless

Minoxidil is an antihypertensive medication and can cause flushing in the face. The flushing can also be an allergic reaction. See your doctor, or reduce the dose back to the 2% and see what happens.

Body Dysmorphic Syndrome reflects people who have Body Dysmorphic Disorder (BDD). These people think about their real or perceived flaws for hours each day. They can’t control their negative thoughts, and don’t believe people who say they look fine since they think of themselves as deformed. Their thoughts often cause severe emotional distress and interfere with their daily functioning. They may miss work or school, avoid social situations, and isolate themselves. They even hide from family and friends, because they fear others will notice their flaws. We see this all of the time in young men with hair loss, and internet forums are replete with these men who are reaching out for help from peers, often without much benefit. Suicide is a common consideration, and when I see this from young men on hair loss forums (which I actively participate in), I often reach out to them. Here are two courageous young men who came forward to speak about it on Reddit:

Balding is the only thing I truly hate about myself from tressless

Being Ugly from tressless

Hello, I am not sure what to do now.

I am a 20-year-old male currently suffering with AGA. I have frontal and crown diffuse thinning. I was on (brand name) Finasteride for about a year, but my hair loss continued. I then switched to (brand name) Dutasteride. No sides and am currently on 1 gram a day rather than 0.5mg. Been on it for nearly 10 months.

All this, yet my hair continues to fall. I can’t use Minoxidil because I am required to look very tidy every day for work related matters. Minox causes a lot of dandruff and makes what’s left of my hair feel coarse and dry.

What can I do? I have been reading up on a famous hair transplant doctor and he mentions how he prescribed a very low dose of around 2.5 – 5mg of Loniten to his patients, and it apparently was very successful. I know of the dangers that come with this drug, though I am prepared to test the waters for a trial with a low dose of around 2mg. This is all I know of that can help. If you know anything else to help I would appreciate it!

You could use topical Minoxidil at night only after a shower, and then shower it off during the daytime. That is as effective as twice a day use.  Oral Minoxidil as you suggest might also work, and in many countries it is the drug of choice.