In Vitro DHT Blocker vs In Vivo DHT Blocker

Can a potential natural supplement not be a DHT blocker in vitro (in a petri dish) but be a DHT blocker in vivo (in the body)?

Also, if Propecia only blocks about 70% of type II 5 alpha reductase, why doesn’t it block the rest if finasteride is meant to block 5ARII?

Is MPB only about blocking DHT or is there more to the story? For example, if we could block 100% of DHT, would our hair loss be blocked?

The things we see in petri dishes and live animal subjects do differ, however, I would want to know specifically what you are asking (a directed question of course).

There is more to balding than DHT alone, but the more of the receptor that is blocked, the better the drug will work. That is why many people like dutasteride as the block gets up to 85% or more, but as I’ve pointed out — at what price? If you became sterile from a high DHT block (I am not saying that it will happen, but lets say hypothetically) the outcome is priceless (negatively speaking).