Blood Flow Stimulators and Hair Loss

I have question(s) that are part product and part physics inquiry:

1. I have used Nano shampoo for several years, and I’m not sure if its effective or not – any thoughts?
2. If using a liquid topical (minoxidil, nioxin, etc) would it be best to apply the topical AFTER wetting your hair completely so that ones hairs do not absorb/wick the topical up onto the hairs, so the wet hair will minimize the ability of dry hair to draw/wick topical fluid away from the scalp?
3. Are there any mild blood flow stimulators you would recommend similar to Retin-A though not as irritating/burning as you repeatedly advise you are not a fan of with Retin-A? Is this the same mechanism the product Procede uses?

(I’m hoping the creativity of my no.2 physics question makes my submission worthy of a response and/or post.)

Thank you!

1. Probably not. No shampoo will cure balding or help with hair loss. Hair loss is genetic in 99% of men. You can use any shampoo you wish, but it will not help with hair loss.
2. It is my understanding that the foam version of minoxidil works best with respect to absorption.
3. Retin-A (tretinoin) does not work for treating hair loss. It is a mild acid that produces a skin irritation that some believe would help when used with minoxidil, because it might make the skin absorb the minoxidil better. There is no clinical evidence of this actually helping grow more hair. In my opinion, you are just irritating your skin. Procede contains thioglycolic acid, which you can learn more about at Wikipedia.