Covid-19 and androgens with DHT blockers

In an interesting article in the Hair Transplant Forum by Nicole Rogers, M.D., has a review of the association of the existence of androgens in men who were infected with severe cases of Covid-19 suggested a relationship between the two. “This protease has a 15 base pair androgen response element, and in humans, androgens are the only know transcription promoters for the TMPRSS2 gene. The ACE2 receptor, which is also a route of COVID entry, is also mediated by androgens.”

Men with balding may have had an increased risk to the Covid-19 virus and severe disease.  Women, of course, don’t have the androgens and it is possible that their estrogen protects them against the virus. There is also a suggestion that men who take androgen blocking medications like finasteride, dutasteride, Spironolactone, Enzalutamide and even canabidoil  might help mitigate the severity of the disease. This is all hypothetical as there is no direct evidence for this in studies that have been done to date. The date has probably been collected but not looked at with this in mind.