Depression from Finasteride?

Dr. Rassman,

Thanks for running this blog, it really helps soo many people. My question is concerning finasteride on depression. I am currently in graduate school and losing hair since 6-7 years. The hairloss has been really significant the last 8 months. I started taking proscar, 1.25mg, since a month ago. I stopped once in between because I was feeling down a bit. When I started taking it again 15 days ago with lower dosage, I again felt a little down. I have never imagined that I could get depressing feelings but I am almost positive its the drug.

What do you know on this matter? How many of your patients felt this way? And when I say depressed-its really not that bad but I am not my regular self.

Thanks

I have not seen this side effect and I do prescribe finasteride to a large number of patients. I have received comments from some patients that they do not ‘feel’ the same. I tried to pin that feeling down, but I do not have it surrounded. Clearly, the decision to take the medication must be weighted against the liability of not having it on board. The same recommendation applies to depression, which has been reported in the literature:

• PubMed – Finasteride induced depression: a prospective study
• FindArticles – Finasteride is used in the treatment of adrogenetic alopecia and has been shown to have minimal adverse effects