Does Dutasteride Produce More Estrogen?

Hi Doc,

I have been on propecia for 15 months with no results and less hair. I really want to try my luck with Advodart or Dutasteride. I just want to know if this produces more estrogen? If so is there risk for blood clots or stroke with dutasteride? I really would appreciate your opinion on the switch and lethal concerns . Thanks so much for your time.

It appears that there is a competitive effect of DHT and estrogen, so if you block DHT with any DHT blocker such as dutasteride or finasteride, the estrogen levels will rise. As far as I am aware, the increased risk of clots or stroke is negligible, but I’m not well versed in everything dutasteride as I do not regularly prescribe it at this point.