Dutasteride, Finasteride, and the CYP3A4 Enzyme
Doctor,
I have read that Dutasteride is metabolised by the CYP3A4 enzyme. I am taking Acomplia (obesity treatment drug) which is a CYP3A4 inhibitor and I have read that has been proved that, in combination with CYP3A4 inhibitor, Dutasteride level in the blood have raised Would this mean than Dutasteride would be ineffective in my case? Would the same be for Propecia?Thanks very much
Drugs like this (metabolized by CYP3A4) may impact liver metabolism and therefore impact the length of action of other drugs in your body. Take note of the following diseases: impaired liver or kidney function. For finasteride, the presence of epilepsy may put you at risk with this drug. It drug may have side effects with antifungal, HIV, antibiotics, antidepressive medications.
I found nothing about dutasteride, but I would imagine the same rules apply as discussed above.
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