Genes and Genetic Hair Loss

I know male pattern baldness is polygenic with multiple genes that contribute to the disease from both the mother and fathers side but i was just wondering with the news that the androgen receptor gene, is on the X chromsome given from mother to son.

Should we assume that mothers genes means “mother’s father” or generally speaking the whole maternal side of the family, which would include the mother’s brothers, uncles, and grandparents…..

I emailed regarding a similar topic and you mentioned that you could not comment on the whole androgen receptor gene article since its all new and i respect that but my main question has to do with when someone says “mothers genes”, should we assume this is exclusive to the mother’s father and that a male should look at his mother’s father to see what his hair will be similar to in the future or is it likely the other males on the mothers side have much influence also …………

Can an individual have the genetic susceptability and partly have some of the genes for MPB but for one reason or another it does not get experessed.

Thanks for your response

You have an assumption here that is confusing you. This is not an on/off gene. Gene expression can skip generations and there are variations in the way the gene is actually expressed. This makes your question moot to some degree, particularly if the X Chromosome comes from the mother’s father.

Yes, having the gene and having the gene expressed are different. We really do not understand the issue of expression or the various families that skip generations before the expression shows.