Is Finasteride Evenly Distributed in a Proscar Tablet?

I would like to thank you for this very useful resource, and your consideration of submmited questions. I have a question about Proscar- since Proscar tablets are not scored four ways- is the finasteride distributed equally throughout the pill, in other words could their be more potent peices of the pill. This was a concern I had about switching to proscar. Are you aware if the pills have an equall distribution of finasteride? It seems like they may not since they are designed to be halved not quartered.

I can not imagine why Merck would weight the active ingredients in a tablet of Proscar (finasteride 5mg). I can’t say with 100% certainty, but I’d believe the distribution is fairly even throughout, particularly since the pill is likely homogenized. If it’s not perfect, it would probably be within a very small fraction of a percent difference. The Proscar isn’t scored, so you will likely get a little more of less each day anyway unless you somehow manage to get a perfect cut on an odd-shaped pill (see image at right). It’s a good question and although I did a little bit of research on it, I couldn’t find the absolute answer for you.

There’s an interesting thread at Drugs-Forum.com about splitting pills and ingredient distribution that you might find useful.