Keeping the dying hair growing

Hello Doc, I’m 26 and taking minoxidil twice a day, finasteride, and doing microneedling twice a day.  I take other medications as well. I will not quit medication because of the hair loss that I could get. Could you kindly tell from your point of view. What could be the reason of such an extremely fast diffuse thinning. I have developed a great deal of reversal from my Norwood Class 6 pattern of extreme thinning.  Many of the hairs got thicker and new hairs grew out.  Could the new regrowth cause the hair to thicken in next cycle? I know that is 6 months progress but maybe your experience give me more hope :) Number of new hairs is quite big but they do not cover scalp completely. Is the diameter of each hair a key to success ? What can i expect ? Should I change finasteride to dutasteride or fin will be sufficient?

I saw your photos on a previous post on reddit and you indeed did partly reverse extensive thinning of the Norwood Class 6 pattern of balding showing before you started treating it. You asked a complex question. Hair growth (Anagen) seems to be induced by wound healing (microneedling) in early balding or thinning but without constant stimulus, I believe that these hairs are eventually doomed. I believe that ingrained in each hair is a biologic clock that dictates the number of hair cycles a hair has when exposed to DHT. This can be altered with drugs and certainly its environment (hormones). Estrogens, for example, when present in significant concentrations without large amounts of testosterone (most females), seem to dictate a different number of hair cycles (women don’t develop Male Patterned Balding). This is just one example. As many of the readers know, I am working with a major university on a solution that might maintain anagen (hair growth) keeping it in its normal cycle, and possibly re-induce the anagen cycle again to the same hair when it goes through telogen. In a male, a normal hair cycle might be 2 – 3 years, so it will take time for us to know. Until we try it in humans, I can’t comment further.  We intend to use this discovery in a clinical trial sometime this year and from it, a new treatment for hair loss may arise.