Minoxidil Response?

My situation is that I used minoxidil for 1.5 years, so imagine all that time I wasn’t a responder. Can it make my hair worse since I’m just applying alcohol all the time?  I’m asking about my situation cause I have been on fin and min and my hair is worse. 

If you used topical minoxidil, only 40% of men have the enzyme in their scalp to convert minoxidil to minoxidil sulfate, the active form of minoxidil; however, if you have taken it orally, 100% of men should get some response to the drug because the liver creates minoxidil sulfate, the active form of the drug. If you had no response to the oral, then you are not a minoxidil responder.