Propecia and the Liver

Hi Dr. Rassman,

In an earlier post you said that it is safe to take accutane and propecia concurrently because they do not interact. However, is it possible taking both at the same time will lead to some kind of liver damage? Another, related question is: how taxing on the liver is propecia?

Thanks in advance for your reply!

The combination of these two medications is not reported to be causing any liver problems. Propecia (finasteride), like many other medications, is metabolized in the liver. Metabolism of this medication in the liver does not affect the function of the liver in normal individuals. If you have severe liver insufficiency, doctors may need to adjust the dose of Propecia, as well as any drug that gets metabolized in the liver.