Silibinin and Propecia

Is it true that Silibinin inhibits cytochrome P450 enzymes? I take Propecia but also make my own herbal tea from milk thistle seeds and loose horsetail, mainly for the health of my liver and to get some extra silica. If Silibinin does inhibit cytochrome P450 enzymes then is a waste of time taking propecia? Moreover, do you know of any other plants that inhibit cytochrome P450 enzymes. Any comments would be appreciated.

Sorry, this is out of my scope of expertise. The best I could do is offer you some links I found via Google (like here or here), but I’m sure you could do the same thing. I’m not familiar with silibinin or the cytochrome P450 enzymes.

One thing I can point out though is that the statement in Wikipedia about silibinin inhibiting the P450 enzymes is unsourced, meaning there is no valid reference explaining where that information came from. I assume you (or someone on a forum) saw that mentioned in Wikipedia, which prompted your initial email. Just food for thought.