Spironolactones and Hair Loss in Women

Are you familiar with using spironoclactone topically for hairloss???? one DR. said it might be the closet thing to cure we have. IT is antiandrogen , which stops DHT at the point on scalp with attacking the follice. I would like to know if you think it worth trying in a lotion on the scalp??? Please respond With you professional opinion. THANKS

Yes, I am familiar with Spironolactones use for hair loss. They have been around for some time. Medline states “Spironolactone, a ‘water pill,’ is used to treat high blood pressure and fluid retention caused by various conditions, including heart disease. It causes the kidneys to eliminate unneeded water and salt from the body into the urine. Spironolactone is also used to treat certain patients with hyperaldosteronism and in certain patients with low potassium levels.”

This is a potent medication and has had some reported impact on fascial hair in women. There are some doctors who use this in conjunction with other medications including Minoxidil, which is an anti-hypertensive medication. Although side effects from spironolactone are not common, they can occur and include: upset stomach, vomiting, diarrhea, stomach pain, frequent urination, dizziness, headache, enlarged or painful breasts, irregular menstrual periods, drowsiness, muscle weakness or cramps, rapid, excessive weight loss, fatigue, slow or irregular heartbeat, sore throat, unusual bruising or bleeding, yellowing of the skin or eyes, skin rash, vomiting blood, fever, and confusion. I do not believe that this is a viable treatment for hair loss as there is no objective evidence that it works in female hair loss, but it is used by some doctors to treat women with hair loss.