Topical finasteride with microneedling, what happens?
I was wondering if using a derma roller increases the probability of excessive absorption of topical finasteride, and thus the risks of averse reactions? If yes, what would be a good strategy to avoid this? For example, could someone simply not use topical finasteride on the day they use the derma roller? But since the effects of the derma roller last for more than one day, wouldn’t the risk of increased averse reactions from topical finasteride still be present in the following days?
I hope that you are aware that topical finasteride does go significantly systemic. The graph shows that even small doses of finasteride raise the DHT levels in your blood, so you might as well take the pill so that, at the least, you are in control of what dose you are delivering to your body. (Reference Perfect Hair Health). This is why I use the Liposomal Topical Finasteride, which largely stays in the scalp, with less than 20% going systemic. The dermaroller probably increases systemic absorption.
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