What Do You Think About Taking 1.25mg Finasteride Twice Daily?

Dear Dr. Rassman:

I am curious to know what you think about taking 1/4 of a dose of Proscar twice daily as a way to counteract its short half-life thereby theoretically increasing its efficacy by increasing its duration sytemically?

There is no evidence that more finasteride is better than the 1mg dose. I do not see a problem with it provided that it does not increase any side effects.