https://www.oatext.com/Long-term-(10-year)-efficacy-of-finasteride-in-523-Japanese-men-with-androgenetic-alopecia.php
RESULTS: We evaluated the long-term (10-year) efficacy and safety of AGA treatment with 1 mg/day finasteride in a large study population (532 patients), as the first study of this kind in Japan, to our knowledge. A high objective efficacy was demonstrated by the MGPA, which revealed improvement and prevention of disease progression in 99.1% of the 532 Japanese men with AGA treated with 1 mg/day finasteride for 10 years.
SEXUAL FUNCTION: In the investigation in 40 years or older of Asians, the incidences of decreased libido and erectile dysfunction were 6.0–38.7% and 40.6–70.0%, respectively [29,23]. Overall, the adverse reactions were all mild, and the incidence was lower than the generic incidence of decreased libido and erectile dysfunction in Asians. As adverse reactions were recorded by patients in a subjective questionnaire, the result was thought to be slightly different from the correct number of adverse reactions in this study
Dr. Rassman’s Comment: The efficacy of long term finasteride treatment has been published many times. When compared side-by-side with men who did not take finasteride, the results show that men with genetic balding hold on to more hair over time than the non-finasteride counterparts. The issue of sexual dysfunction is briefly discussed and the comment that the sexual side effects of age parallel the sexual side effects while on the drug (just slightly less according to this study). There were no cases of Past-finasteride syndrome reported in this study, a significant point.
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The hairline belongs about one finger breadth above the highest crease of the furrowed brow. This man will find that his hairline was transplanted unnaturally too high. I believe it belongs about 1 inch lower than the surgeon placed it about where I placed the arrow. In addition, the hairline is lower on the patient’s right side.
Is it true that if I stop using DHT blocking shampoos I will lose hair, even if my hairline may just be matured?
There is no effective DHT blocking shampoo on the market. It is not easy to get a DHT block from a shampoo that you wash off of your head
Do you believe that it stays effective long term? (Say more than two years) Or will it lose effectiveness compared to the oral form? I am 22 years of age and considering taking topical instead of oral. Let me know what you think.
If you are asking me if you continue to apply it for 2 years or more, will it still be effective. The answer is yes!
To those who are just using Minoxidil and micro-needling only. I am just speaking from my own experience but eventually whatever gains you get from the two will not last, at least it didn’t for me. But I have continued to persist with it even though it continued to get worst. I am 39 and now starting on topical finasteride for the first time
I am not surprised that even if you got all of your hair back, once a single hair cycle completed (2-3 years) the balding would have returned to where it is now. If the topical finasteride fails and you want your hair back, a hair transplant is a sure thing for this type of balding.
Over the past 38 years, the sperm count measured at Mt. Sinai Hospital and elsewhere has dropped 58%. Dr. Swan reported this alarming statistic on the BBC. She believes that this change must be due to environmental factor such as plastics and other chemicals which are now in our bodies. In addition to the number of sperm produced per cc of ejaculate, the quality of the sperm is also down as more and more embryos are developing with congenital problems which are now being identified in the offspring of our children. Dr. Swan believes that these changes are probably permanent and correction might take a few generations to correct.
I started using minoxidil earlier this year for my temporal recession (I’ve already been on finasteride for a while). I’ve decided that I would like to pursue a FUE transplant for my temples, eventually. When I think about it, it seems to make sense to stop minoxidil and to wait for the dependent hairs to fall out before getting the transplant. That way, the hairline that is not dependent on topicals emerges, and the transplant can fill those areas as fully as possible. Does that make sense? I haven’t had an initial consult yet and I think I may want to even put that off until after I stop the minoxidil so I can get an evaluation for my hairline without it and then pursue a transplant shortly after.
I tell my patients to continue it for up to 3 days before the hair transplant and then pick it up again at about 1-2 weeks after the transplant so you don’t lose the minoxidil dependent hairs.
The results show that the hair is returning. You may find that it will not grow very long of as in some finasteride users, reverse the process. Wait another year and then see if you can get length on it. Consider adding minoxidil and possibly microneedling to the area. Look this combination up on this website (see search bar) and see some amazing results with the combination of finasteride, minoxidil and microneedling.
There is a lot that is not known about microneedling. In theory, once you get the hair growing and healthy, you might be able to stop it and then wait a full hair cycle before worrying if the hair will fall out or not. Alternatively, you can significantly reduce the amount of microneedling like once a month or once every other month just to keep the stimulus there. IF any reader has more information about this, I would like to hear from them. Transplants go much needler than the microneedle so scarring should not be a problem, in theory.
It doesn’t. If you only lose “some” of your hair, doesn’t mean you won’t lose anymore. Just means your hair loss hasn’t advanced to that point yet.
Of course it exists. I have a mature hairline and had balding in my crown which I treated with a hair transplant so now I am just a normal hairy guy.
I’m 21 and I’ve used minoxidil in the past (foam and liquid), but it was just too much of a hassle to apply consistently so I never saw any gains. Has anyone here used oral minoxidil with good results?
Oral minoxidil can be effective for male patterned hair loss. For many years, poorer countries have been using it successfully for male patterned hair loss before finasteride was released in their country. In India, for example, many people couldn’t afford Propecia and genetic finasteride wasn’t available so oral minoxidil was the only drug for hair loss.
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