[May 2019 Study] Effectiveness and Safety of Low-Dose Oral Minoxidil in Male Androgenic Alopecia:
TL;DR – 2.5mg and 5mg dose of oral minoxidil found safe and effective in 41 male patients. 90% of patients had marked improvements.
Of 41 male patients (mean age, 33.3 years; range, 20–55 years) with androgenetic alopecia who received oral minoxidil monotherapy (2.5 or 5 mg daily) for a minimum of 6 months, 37 patients (90.2%) had clinical improvement, which was marked in 11 of them (26.8%). Only 4 patients (9.8%) demonstrated stabilization of their alopecia; however, none of these patients experienced worsening of the condition. Adverse effects included hypertrichosis (24.3%), lower limb edema (4.8%), and shedding (2.4%).
Results of this retrospective study indicated that oral minoxidil at 2.5 mg and 5 mg daily can be an effective therapy for male androgenetic alopecia, with a mild side-effect profile.
– InYoung Kim, MD, PhD