My MD has me on Avodart 0.5 MG once daily for hair loss and I have been taking it for about 20 months now and it seems to work better than the Proscar that I was taking the five years before.I just had my second HTP a couple of months ago and the HT doctor said the Avodart that I’m taking stays in my system fot 5-7 days and that I should not need to take it daily to have the same results. Where do you stand on it?
Avodart (dutasteride) does stay in your system for several weeks (5 weeks are reported for half of the drug to disappear from your system). In other words, if you take Avodart today only, half of the drug will be in your body in 5 weeks. In fact, the drug will still be detectable in your body for up to 6-12 months.
I do not personally recommend Avodart to my patients, because it is not proven safe for treating hair loss in younger men (the drug is a prostate medication, so the FDA approvals were based on tests of those men in an older age group). There are reports of sterility with this drug on men. I do have a handful of patients that choose to take Avodart despite my concerns, but that is on an individual basis. Likewise, my feeling on it is that you need to address these concerns with your doctor and decide on the appropriate treatment plan after understanding all the risks and benefits associated with its use. That stands true for all other drugs and medical treatments.
In general (to confuse the situation even further), the 0.5mg dose of Avodart is not generally used for hair growth, as 2.5mg is shown to produce a better effect. However, the 2.5mg will increase the side effects and the risks associated with it as well. All that is just more to discuss with your doctor. Read this study published in the Journal of the American Academy of Dermatology for more info — Dutasteride vs. Finasteride.