I was reading up on a few dutasteride studies and was curious what your thoughts were about the recommended dosage of dutasteride given it’s rather extended half life. https://academic.oup.com/jcem/article/89/5/2179/2844345 for example. Clark noted that the DHT suppression in patients after drug cessation for .5mg dutasteride only had a minor deteriation after 2 weeks with greater DHT […]
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Does dutasteride cause permanent fertility though? I want to stop a month before trying to get a child, will this be okay? Stop it and get a sperm count with your doctor. The half life of this drug is 5-6 weeks so it will take many months for it to be out of your body, […]
I’ve been prescribed and have been taking dutasteride for about 3.5 years in hopes of delaying and preventing hair loss. I’ve been incredibly happy with the results of my hair, but have become concerned about the potential for long-term side effects. I have been considering a transplant, but currently have good coverage with the dutasteride. […]
The safety of dutasteride in young men with hair loss has not been determined as this drug is not FDA approved. Start with finasteride which is almost as effective (70% vs 85% of the competitive inhibition at the hair follicle level)
If I had side effects on dutasteride, would it take longer for them to go away after quitting use due to dutasteride’s long half-life? Yes, most probably! We know the half life is in weeks (half life in the blood) but the half life in the body’s tissues are much longer (I don’t know those […]
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746394/
Taking testosterone will accelerate genetic hair loss regardless of the medications you are on to stop that from happening
I’m reading on the package of finasteride accord and it says that it lowers the sperm quality and that infertility is a possibility. Would I be risking going infertile if I were to take finasteride for 10 years? Infertility would be a very remote possibility. I looked into this when my son’s sperm count dropped […]
I currently do 1mg fin a day, so 7mg a week. I’ve been thinking of starting 0.5mg dut once a week, so a step up on your scale I guess. My main question is this; I’m 23 amd started a year ago and have had fair results. Should I wait until I start losing ground […]
I’m about soon to reach two years of Finasteride (1.25 mg per day) usage. My hair loss has continued and I now have a diffused crown, which I did not have when I started the treatment. I’m gonna reach out to my doctor and ask for a prescription of Dutasteride. It would be great if […]
Good early results from 18 weeks using dutasteride. I expect more reversal over the end of a years use. Dutasteride blocks the enzyme 5 alpha reductase by competing with it at the hair receptor sites and it is 80-85% effective, while finasteride is 70% effective. The problem with dutasteride, because it is more effective is […]
Hi Dr. Rassman, i have a couple of questions. I’ve been on fin for almost 4 years and I think I’m seeing thinning the frontal area if I get a prescription for dutasteride is it likely I will respond to dutasteride? And if I take my last Finasteride pill and then, the next day I […]
https://www.sciencedirect.com/science/article/abs/pii/S0190962206012874 Other articles show that finasteride effects t 6+ months show that the difference between the two narrows.
Very nice responsive treatment. Keep it up and all of the balding may be gone shortly.
https://pubmed.ncbi.nlm.nih.gov/28632494/ Conclusion Our findings suggest that long-term dutasteride therapy produces worsening of ED, reduced T levels and increased glucose, HbA1c and alters lipid profiles, suggesting induced imbalance in metabolic function. We strongly recommend that physicians discuss with their patients these potential serious adverse effects of long-term dutasteride therapy prior to instituting this form of treatment.
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