Yes, fatty liver can cause hair thinning and it may reflect some other condition going on that could precipitate genetic balding if you have the genes for balding. For most men (98%), thinning and hair loss is genetic. Here is an article reflecting the general safety of minoxidil with regard to liver toxicity: https://www.ncbi.nlm.nih.gov/books/NBK548394/
Oral finasteride is much better than topical because it cover your entire head, even the hairs that you can’t see which are going into the early part of miniaturization. The topical only works where you apply it and it is VERY expensive but unless it is the liposomal preparation, it can go systemic. Example a one year supply of oral generic finasteride is $27 at Costco but a local liposomal topical finasteride (a type of finasteride that stays in the skin0 runs about $60-70/bottle which comes out to treating your hairline for about $800/year.
I’ve read about someone microneedling daily, with a dermastamp I think, at 1.5mm, with great results. Do you think this is unreasonable or even risky? Or just ineffective or suboptimal? It did seem to work for that person.
There is no reason to microneedle daily. There is a wound healing cycle that microneedling invokes and this can be stimulated once a week reasonably well.
Dads apparently been on it for 20+ years and don’t think he’s ever had problems. Says his hair hasn’t changed since he started. Is this any sign it will work/won’t give me side effects? Can’t find anything about this anywhere.
I don’t believe that finasteride responders are an inherited trait
How much hair comes out in the shower in a person not losing hair?
Hair that is shed is not coming out because you shampoo your hair (unless you to it roughly), it comes out because it is either going through its normal telogen cycle or you are losing it from miniaturization or genetic factors. Not shampooing your hair will make no difference in your overall hair volume or hair density across the scalp
Most of the topical finasteride sold today can get through the skin and its not the Liposomal preparation. if the drug gets through the skin into the body and you are known to get side effects with the pill, you will get it with the normal topical finasteride. With the Liposomal preparation; however, the measured maximal absorption for topical liposomal finasteride was reported to be rarely in excess of 18% of the total dose. I hope that language better explains what I know. But I would be happy to review articles you might have as I always keep an open mind. Last week I had a patient with the ethanol/ PG base solution and he had bad sexual side effects and that is why he came to me to get the Liposomal preparation.
A Liposomal preparation of a drug puts the active drug inside very tiny, fat-like particles. This allows more localization of the drug. Men who have measured their DHT levels found that with the topical liposomal finasteride preparations, their DHT levels did not change.
The range where these stem cells are more heavily concentrated is the area between 0.5 and 1.5mm (Click on photo to enlarge). If the needles get into this area, they will produce internal injuries to the fat in this area and that starts the cascade that induces stem cell response. I labeled it “Cycling Stem Cells” in the photo of a graft below. You should also notice that the actual hair shaft goes down much deeper than the Cycling Stem Cell area.
Quick question do baby hairs grow all over head but are mostly apparent around the temples and nape and hairline?
There are short vellus hairs that never grow up and there are hairs that are early in anagen that appear short. I have seen men who get good response from finasteride who show short anagen hairs that will eventually grow out once they have a few months of growth. There are also some short hairs that are at the end of their life and are frequently found in a hairline that is being lost through miniaturization. Is that what you are talking about with the term baby hairs?
Some folks don’t respond to 5AR inhibitors and find no other option but to quit and embrace baldness instead of consider the immunologic possibility of their hairloss. Could Lichen Planus and related illnesses be, in combination or by themselves, be accountable for hairloss on a relevant scale? Why aren’t we discussing this topic more?
The diagnosis of lichen planopilaris is a cause of alopecia. The diagnosis can be made using a trichoscope by seeing perifollicular erythema, milky-red areas, classic white and blue-grey dots. This is an autoimmune disease that kills off the hair. It is more common in women than men, although the diagnosis is being picked up more so in some men lately. If a surgeon doesn’t make the diagnosis and does a hair transplant, the transplant will fail. A costly mistake. A biopsy usually is the final authority for the diagnosis.
You are developing miniaturization leading to corner recession of the hairline. It looks like it may extend to more of the frontal hairline than you are showing here. This is the best time to begin treating it as reversal is possible.
This is an good result in a young man who appears to be responsive to these medications.
Good response from 5 months finasteride, minoxidil and microneedling
Two years of minoxidil foam 5% plus finasteride. You should have comparable photos but the difference is so dramatic, that the look alone says it all
